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2,6-bis(4-chlorobenzylidene)cyclohexan-1-one

  • CAS No.: 18989-82-7
  • Purity: 99%
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Reputable factory supply 2,6-bis(4-chlorobenzylidene)cyclohexan-1-one 18989-82-7 in bulk at low price

  • Molecular Formula: C20H16Cl2O
  • Molecular Weight: 343.252
  • Vapor Pressure: 2.91E-11mmHg at 25°C 
  • Melting Point: 147-148 °C 
  • Boiling Point: 528.7°Cat760mmHg 
  • Flash Point: 220.4°C 
  • PSA: 17.07000 
  • Density: 1.308g/cm3 
  • LogP: 6.21340 

2,6-bis(4-chlorobenzylidene)cyclohexan-1-one(Cas 18989-82-7) Usage

General Description

2,6-bis(4-chlorobenzylidene)cyclohexan-1-one, also known as Muscone, is a synthetic compound commonly used in perfumery for its musky fragrance. It is a cyclic ketone with two benzylidene groups, each containing a chlorine atom, attached to the cyclohexane ring. Muscone is highly valued for its long-lasting and animalic scent, often described as sweet, woody, and musky. Due to its intense fragrance, it is used as a base note in many high-end perfumes and colognes. Additionally, it has been studied for its potential pharmaceutical properties, and it is also used as a flavoring agent in foods and beverages.

InChI:InChI=1/C20H16Cl2O/c21-18-8-4-14(5-9-18)12-16-2-1-3-17(20(16)23)13-15-6-10-19(22)11-7-15/h4-13H,1-3H2

18989-82-7 Relevant articles

Design, synthesis and antimicrobial properties of novel 3,3a,4,5,6,7-hexahydroindazole and arylthiazolylpyrazoline derivatives

Bishnoi, Abha,Singh, Suruchi,Tiwari, Anil K.,Sethi, Arun,Tripathi, Chandrakant Mani

, p. 45 - 52 (2013)

A remarkable diastereoselective synthesi...

Activated charcoal-mediated synthesis of chalcones catalyzed by NaOH in water

Tanemura, Kiyoshi,Rohand, Taoufik

supporting information, (2021/02/27)

A variety of chalcones were synthesized ...

Synthesis of thiazolylidenethiazoloquinazolinone hybrids from monocarbonyl curcumin analogues. Characterization, bio-evaluation and DFT study

Benreka, Soufiane,Kasmi-Mir, Souad,Kirsch, Gilbert,Madi, Fatiha,Zradni, Fatima-Zohra

, (2021/09/03)

Given the diverse pharmacological attrib...

Synthesis and characterization of functionalized NaP Zeolite@CoFe2O4 hybrid materials: a micro–meso-structure catalyst for aldol condensation

Mortezaei, Zohreh,Zendehdel, Mojgan,Bodaghifard, Mohammad Ali

, p. 2169 - 2193 (2020/01/29)

In this work, magnetic nanocomposite of ...

Green, rapid, and highly efficient syntheses of α,α′-bis[(aryl or allyl)idene]cycloalkanones and 2-[(aryl or allyl)idene]-1-indanones as potentially biologic compounds via solvent-free microwave-assisted Claisen–Schmidt condensation catalyzed by MoCl5

Bakhshi, Reza,Zeynizadeh, Behzad,Mousavi, Hossein

, p. 623 - 637 (2019/08/26)

A new, green, and highly efficient proto...

18989-82-7 Process route

1-(Trimethylsilyloxy)cyclohexene
6651-36-1

1-(Trimethylsilyloxy)cyclohexene

(acetyloxy)(4-chlorophenyl)methyl acetate
13086-93-6

(acetyloxy)(4-chlorophenyl)methyl acetate

(2E,6E)-2,6-bis(4-chlorobenzylidene)cyclohexanone
18989-82-7,42792-80-3

(2E,6E)-2,6-bis(4-chlorobenzylidene)cyclohexanone

Conditions
Conditions Yield
With boron trifluoride diethyl etherate; In diethyl ether; dichloromethane; at 0 - 20 ℃;
49%
4-chlorobenzylidene dicrotonate

4-chlorobenzylidene dicrotonate

1-(Trimethylsilyloxy)cyclohexene
6651-36-1

1-(Trimethylsilyloxy)cyclohexene

(2E,6E)-2,6-bis(4-chlorobenzylidene)cyclohexanone
18989-82-7,42792-80-3

(2E,6E)-2,6-bis(4-chlorobenzylidene)cyclohexanone

Conditions
Conditions Yield
With boron trifluoride diethyl etherate; In diethyl ether; dichloromethane; at 0 - 20 ℃;
30%

18989-82-7 Upstream products

  • 108-94-1
    108-94-1

    cyclohexanone

  • 104-88-1
    104-88-1

    4-chlorobenzaldehyde

  • 1670-47-9
    1670-47-9

    1,1-diethoxycyclohexane

  • 6651-36-1
    6651-36-1

    1-(Trimethylsilyloxy)cyclohexene

18989-82-7 Downstream products

  • 110049-85-9
    110049-85-9

    cis -2,6-bis-(4-chloro-benzyl)-cyclohexanone

  • 6603-81-2
    6603-81-2

    2,6-Bis- <4-chlor-benzyliden> -cyclohexan-1-ol

  • 110049-85-9
    110049-85-9

    2,6-bis(4-chlorobenzyl)cyclohexanone

  • 54105-30-5
    54105-30-5

    2-Amino-8(4-chlorbenzyliden)3-cyan-4(4-chlorphenyl)-5.6.7.8-tetrahydro-4-H-chromen

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